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1

Advanced Methods for Dose and Regimen Finding During Drug Development: Summary of the EMA/EFPIA Workshop on Dose Finding (London 4-5 December 2014)

Musuamba, FT, Manolis, E, Holford, N, Cheung, SYA, Friberg, LE, Ogungbenro, K, Posch, M, Yates, JWT, Berry, S, Thomas, N, Corriol-Rohou, S, Bornkamp, B, Bretz, F, Hooker, AC, Van der Graaf, PH, Standi

Journal:

CPT: Pharmacometrics & Systems Pharmacology

Year:

2017

Language:

english

File:

PDF, 251 KB

english, 2017

2

Model-Informed Precision Dosing: Background, Requirements, Validation, Implementation, and Forward Trajectory of Individualizing Drug Therapy

Darwich, Adam S., Polasek, Thomas M., Aronson, Jeffrey K., Ogungbenro, Kayode, Wright, Daniel F.B., Achour, Brahim, Reny, Jean-Luc, Daali, Youssef, Eiermann, Birgit, Cook, Jack, Lesko, Lawrence, McLac

Journal:

Annual Review of Pharmacology

Year:

2021

File:

PDF, 661 KB

2021

3

[IEEE Technology (ICAST) - Abuja, Nigeria (2011.11.24-2011.11.26)] 3rd IEEE International Conference on Adaptive Science and Technology (ICAST 2011) - Design, construction and testing of multipurpose energy saving LEDs and its implications on energy crisis in Nigeria

Ogungbenro, Oluwaseyi Akinyele, Ndinechi, Michael C.

Year:

2011

Language:

english

File:

PDF, 262 KB

english, 2011

4

Rainfall distribution and change detection across climatic zones in Nigeria

Ogungbenro, Stephen Bunmi, Morakinyo, Tobi Eniolu

Journal:

Weather and Climate Extremes

Year:

2014

Language:

english

File:

PDF, 1.01 MB

english, 2014

5

Performance of Activated Carbons Derived from Date Seeds in CO 2 Swing Adsorption Determined by Combining Experimental and Molecular Simulation Data

Bahamon, Daniel, Ogungbenro, Adetola E., Khaleel, Maryam, Abu-Zahra, Mohammad R. M., Vega, Lourdes F.

Journal:

Industrial & Engineering Chemistry Research

Year:

2020

Language:

english

File:

PDF, 2.61 MB

english, 2020

6

Synthesis and characterization of activated carbon from biomass date seeds for carbon dioxide adsorption

Ogungbenro, Adetola E., Quang, Dang V., Al-Ali, Khalid A., Vega, Lourdes F., Abu-Zahra, Mohammad R.M.

Journal:

Journal of Environmental Chemical Engineering

Year:

2020

File:

PDF, 2.71 MB

2020

7

Application of optimal design methodologies in clinical pharmacology experiments

Kayode Ogungbenro, Aristides Dokoumetzidis, Leon Aarons

Journal:

Pharmaceutical Statistics

Year:

2009

Language:

english

File:

PDF, 236 KB

english, 2009

8

Population pharmacokinetics and optimal design of paediatric studies for famciclovir

Kayode Ogungbenro, Ivan Matthews, Michael Looby, Guenther Kaiser, Gordon Graham, Leon Aarons

Journal:

British Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 1.89 MB

english, 2009

9

Mean state and kinematic properties of mesoscale convective systems over West Africa

Ogungbenro, Stephen B., Ajayi, V. O., Adefolalu, D. O.

Journal:

Theoretical and Applied Climatology

Year:

2016

Language:

english

File:

PDF, 830 KB

english, 2016

10

Mathematical model of T-cell lymphoblastic lymphoma: disease, treatment, cure or relapse of a virtual cohort of patients

Eymard, N., Volpert, V., Kurbatova, P., Volpert, V., Bessonov, N., Ogungbenro, K., Aarons, L., Janiaud, P., Nony, P., Bajard, A., Chabaud, S., Bertrand, Y., Kassaï, B., Cornu, C., Nony, P.

Journal:

Mathematical Medicine and Biology

Year:

2017

Language:

english

File:

PDF, 4.35 MB

english, 2017

11

Comparison of piperacillin exposure in the lungs of critically ill patients and healthy volunteers

Felton, T W, Ogungbenro, K, Boselli, E, Hope, W W, Rodvold, K A

Journal:

Journal of Antimicrobial Chemotherapy

Year:

2018

Language:

english

File:

PDF, 416 KB

english, 2018

12

The sociopolitical factors impacting the adoption and proliferation of desalination: A critical review

Ibrahim, Yazan, Ismail, Roqaya A., Ogungbenro, Adetola, Pankratz, Tom, Banat, Fawzi, Arafat, Hassan A.

Journal:

Year:

2021

File:

PDF, 10.97 MB

2021

13

Sample-size calculations for multi-group comparison in population pharmacokinetic experiments

Kayode Ogungbenro, Leon Aarons

Journal:

Pharmaceutical Statistics

Year:

2010

Language:

english

File:

PDF, 221 KB

english, 2010

14

How many subjects are necessary for population pharmacokinetic experiments? Confidence interval approach

Kayode Ogungbenro, Leon Aarons

Journal:

European Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 262 KB

english, 2008

15

Optimal Blood Sampling Time Windows for Parameter Estimation Using a Population Approach: Design of a Phase II Clinical Trial

Marylore Chenel, Kayode Ogungbenro, Vincent Duval, Christian Laveille, Roeline Jochemsen, Leon Aarons

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2005

Language:

english

File:

PDF, 344 KB

english, 2005

16

Optimal Design for Multivariate Response Pharmacokinetic Models

Ivelina Gueorguieva, Leon Aarons, Kayode Ogungbenro, Karin M. Jorga, Trudy Rodgers, Malcolm Rowland

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2006

Language:

english

File:

PDF, 211 KB

english, 2006

17

Optimal Design for Multiresponse Pharmacokinetic–Pharmacodynamic Models – Dealing with Unbalanced Designs

Kayode Ogungbenro, Ivelina Gueorguieva, Oneeb Majid, Gordon Graham, Leon Aarons

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2007

Language:

english

File:

PDF, 259 KB

english, 2007

18

Drug–drug interaction predictions with PBPK models and optimal multiresponse sampling time designs: application to midazolam and a phase I compound. Part 1: comparison of uniresponse and multiresponse designs using PopDes

Marylore Chenel, François Bouzom, Leon Aarons, Kayode Ogungbenro

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2008

Language:

english

File:

PDF, 512 KB

english, 2008

19

Drug–drug interaction predictions with PBPK models and optimal multiresponse sampling time designs: application to midazolam and a phase I compound. Part 2: clinical trial results

Marylore Chenel, François Bouzom, Fanny Cazade, Kayode Ogungbenro, Leon Aarons, France Mentré

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2008

Language:

english

File:

PDF, 610 KB

english, 2008

20

Optimisation of sampling windows design for population pharmacokinetic experiments

Kayode Ogungbenro, Leon Aarons

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2008

Language:

english

File:

PDF, 398 KB

english, 2008

21

Sample size/power calculations for repeated ordinal measurements in population pharmacodynamic experiments

Kayode Ogungbenro, Leon Aarons

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2010

Language:

english

File:

PDF, 250 KB

english, 2010

22

Population Fisher information matrix and optimal design of discrete data responses in population pharmacodynamic experiments

Kayode Ogungbenro, Leon Aarons

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2011

Language:

english

File:

PDF, 448 KB

english, 2011

23

Structural identifiability analysis of pharmacokinetic models using DAISY: semi-mechanistic gastric emptying models for13C-octanoic acid

Kayode Ogungbenro, Leon Aarons

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2011

Language:

english

File:

PDF, 945 KB

english, 2011

24

A Semi-mechanistic Gastric Emptying Model for the Population Pharmacokinetic Analysis of Orally Administered Acetaminophen in Critically Ill Patients

Kayode Ogungbenro, Lakshmi Vasist, Robert Maclaren, George Dukes, Malcolm Young, Leon Aarons

Journal:

Pharmaceutical Research

Year:

2011

Language:

english

File:

PDF, 686 KB

english, 2011

25

The population pharmacokinetics of R- and S-warfarin: effect of genetic and clinical factors

Steven Lane, Sameh Al-Zubiedi, Ellen Hatch, Ivan Matthews, Andrea L. Jorgensen, Panos Deloukas, Ann K. Daly, B. Kevin Park, Leon Aarons, Kayode Ogungbenro, Farhad Kamali, Dyfrig Hughes, Munir Pirmoham

Journal:

British Journal of Clinical Pharmacology

Year:

2012

Language:

english

File:

PDF, 3.52 MB

english, 2012

26

Optimal Design of Pharmacokinetic Studies

Leon Aarons, Kayode Ogungbenro

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2010

Language:

english

File:

PDF, 141 KB

english, 2010

27

Intravenous anakinra can achieve experimentally effective concentrations in the central nervous system within a therapeutic time window: results of a dose-ranging study

Galea, James, Ogungbenro, Kayode, Hulme, Sharon, Greenhalgh, Andrew, Aarons, Leon, Scarth, Sylvia, Hutchinson, Peter, Grainger, Samantha, King, Andrew, Hopkins, Stephen J

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2010

Language:

english

File:

PDF, 476 KB

english, 2010

28

The use of a modified Fedorov exchange algorithm to optimise sampling times for population pharmacokinetic experiments

Kayode Ogungbenro, Gordon Graham, Ivelina Gueorguieva, Leon Aarons

Journal:

Computer Methods and Programs in Biomedicine

Year:

2005

Language:

english

File:

PDF, 214 KB

english, 2005

29

A program for individual and population optimal design for univariate and multivariate response pharmacokinetic–pharmacodynamic models

Ivelina Gueorguieva, Kayode Ogungbenro, Gordon Graham, Sophie Glatt, Leon Aarons

Journal:

Computer Methods and Programs in Biomedicine

Year:

2007

Language:

english

File:

PDF, 712 KB

english, 2007

30

A semi-mechanistic gastric emptying pharmacokinetic model for 13C-octanoic acid: An evaluation using simulation

Kayode Ogungbenro, Leon Aarons

Journal:

European Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 507 KB

english, 2012

31

[IEEE Technology (ICAST) - Abuja, Nigeria (2011.11.24-2011.11.26)] 3rd IEEE International Conference on Adaptive Science and Technology (ICAST 2011) - Hardware description language (HDL): An efficient approach to device independent designs for VLSI market segments

Chinedu, Okafor Kennedy, Genevera, Ezekwe Chinwe, Akinyele, Ogungbenro Oluwaseyi

Year:

2011

Language:

english

File:

PDF, 510 KB

english, 2011

32

Physiologically based pharmacokinetic modelling of methotrexate and 6-mercaptopurine in adults and children. Part 2: 6-mercaptopurine and its interaction with methotrexate

Ogungbenro, Kayode, Aarons, Leon

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2014

Language:

english

File:

PDF, 846 KB

english, 2014

33

Physiologically based pharmacokinetic modelling of methotrexate and 6-mercaptopurine in adults and children. Part 1: methotrexate

Ogungbenro, Kayode, Aarons, Leon

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2014

Language:

english

File:

PDF, 725 KB

english, 2014

34

Protective Effects of Extracts of Vernonia amygdalina, Hibiscus sabdariffa and Vitamin C against Radiation-induced Liver Damage in Rats

ADARAMOYE, Oluwatosin, OGUNGBENRO, Bayo, ANYAEGBU, Oluchi, FAFUNSO, Michael

Journal:

Journal of Radiation Research

Year:

2008

Language:

english

File:

PDF, 327 KB

english, 2008

35

A physiologically based pharmacokinetic model for Valproic acid in adults and children

Ogungbenro, Kayode, Aarons, Leon

Journal:

European Journal of Pharmaceutical Sciences

Year:

2014

Language:

english

File:

PDF, 810 KB

english, 2014

36

Sample Size Calculations Based on Generalized Estimating Equations for Population Pharmacokinetic Experiments

Ogungbenro, Kayode, Aarons, Leon, Graham, Gordon

Journal:

Journal of Biopharmaceutical Statistics

Year:

2006

Language:

english

File:

PDF, 162 KB

english, 2006

37

An Effective Approach for Obtaining Optimal Sampling Windows for Population Pharmacokinetic Experiments

Ogungbenro, Kayode, Aarons, Leon

Journal:

Journal of Biopharmaceutical Statistics

Year:

2009

Language:

english

File:

PDF, 437 KB

english, 2009

38

Translational pharmacokinetics: challenges of an emerging approach to drug development in stroke

Greenhalgh, Andrew D, Ogungbenro, Kayode, Rothwell, Nancy J, Galea, James P

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2011

Language:

english

File:

PDF, 690 KB

english, 2011

39

[IEEE 2006 Conference on Optoelectronic and Microelectronic Materials and Devices - Perth, Australia (2006.12.6-2006.12.8)] 2006 Conference on Optoelectronic and Microelectronic Materials and Devices - Elements of Nanophotonics: Photonic Crystals, Photonic Wires, Metamaterials and More

de la Rue, Richard M., Khokhar, Ali Z., Lahiri, Basudev, Sorel, Marc, Rahman, Faiz, Gnan, Marco, Chong, Harold M. H., Pottier, Pierre, Zain, Ahmad R. Md, Ironside, Charles N., Ogungbenro, J. Wale, Joh

Year:

2006

Language:

english

File:

PDF, 262 KB

english, 2006

40

Incorporating Correlation in Interindividual Variability for the Optimal Design of Multiresponse Pharmacokinetic Experiments

Ogungbenro, Kayode, Graham, Gordon, Gueorguieva, Ivelina, Aarons, Leon

Journal:

Journal of Biopharmaceutical Statistics

Year:

2008

Language:

english

File:

PDF, 507 KB

english, 2008

41

Precision criteria to derive sample size when designing pediatric pharmacokinetic studies: Which measure of variability should be used?

Salem, Farzaneh, Ogungbenro, Kayode, Vajjah, Pavan, Johnson, Trevor N., Aarons, Leon, Rostami-Hodjegan, Amin

Journal:

Journal of Clinical Pharmacology

Year:

2014

Language:

english

File:

PDF, 525 KB

english, 2014

42

Methods and software tools for design evaluation in population pharmacokinetics-pharmacodynamics studies

Nyberg, Joakim, Bazzoli, Caroline, Ogungbenro, Kay, Aliev, Alexander, Leonov, Sergei, Duffull, Stephen, Hooker, Andrew C., Mentré, France

Journal:

British Journal of Clinical Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.31 MB

english, 2015

43

A Physiologically Based Pharmacokinetic Model for Clobazam and Stiripentol in Adults and Children

Ogungbenro, Kayode, Aarons, Leon

Journal:

Pharmaceutical Research

Year:

2015

Language:

english

File:

PDF, 909 KB

english, 2015

44

Model-Based Evaluation of the Impact of Formulation and Food Intake on the Complex Oral Absorption of Mavoglurant in Healthy Subjects

Wendling, Thierry, Ogungbenro, Kayode, Pigeolet, Etienne, Dumitras, Swati, Woessner, Ralph, Aarons, Leon

Journal:

Pharmaceutical Research

Year:

2015

Language:

english

File:

PDF, 1.05 MB

english, 2015

45

Empirical and Semi-Mechanistic Modelling of Double-Peaked Pharmacokinetic Profile Phenomenon Due to Gastric Emptying

Ogungbenro, Kayode, Pertinez, Henry, Aarons, Leon

Journal:

The AAPS Journal

Year:

2015

Language:

english

File:

PDF, 514 KB

english, 2015

46

Sample Size/Power Calculations for Population Pharmacodynamic Experiments Involving Repeated-Count Measurements

Ogungbenro, Kayode, Aarons, Leon

Journal:

Journal of Biopharmaceutical Statistics

Year:

2010

Language:

english

File:

PDF, 522 KB

english, 2010

47

Sample Size Calculations for Population Pharmacodynamic Experiments Involving Repeated Dichotomous Observations

Ogungbenro, Kayode, Aarons, Leon

Journal:

Journal of Biopharmaceutical Statistics

Year:

2008

Language:

english

File:

PDF, 103 KB

english, 2008

48

Design of population pharmacokinetic experiments using prior information

Ogungbenro, K., Aarons, L.

Journal:

Year:

2007

Language:

english

File:

PDF, 719 KB

english, 2007

49

Application of a Bayesian approach to physiological modelling of mavoglurant population pharmacokinetics

Wendling, Thierry, Dumitras, Swati, Ogungbenro, Kayode, Aarons, Leon

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2015

Language:

english

File:

PDF, 1.57 MB

english, 2015

50

Study design and population pharmacokinetic analysis of a phase II dose-ranging study of interleukin-1 receptor antagonist

Ogungbenro, Kayode, Hulme, Sharon, Rothwell, Nancy, Hopkins, Stephen, Tyrrell, Pippa, Galea, James

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2016

Language:

english

File:

PDF, 1.34 MB

english, 2016